During the late 1950s, Rivers appeared in a short-run play, Driftwood, playing a lesbian with a crush on a character played by a then-unknown Barbra Streisand. The play ran for six weeks. In 1961, Rivers briefly performed on stage in Chicago at The Second City comedy club. Rivers performed in numerous comedy clubs in the Greenwich Village area of New York City in the early 1960s, including The Bitter End and The Gaslight Cafe, before making her first appearances as a guest on the TV program The Tonight Show originating from New York, hosted at the time by Jack Paar

By 1965, Rivers had a stint on Candid Camera as a gag writer and participant; she was "the bait" to lure people into ridiculous situations for the show. She also made her first appearance on The Tonight Show with new host Johnny Carson, on February 17, 1965. During the same decade, Rivers made other appearances on The Tonight Show as well as The Ed Sullivan Show, while hosting the first of several talk shows. She wrote material for the puppet Topo Gigio. She had a brief role in The Swimmer (1968), starring Burt Lancaster. A year later, she had a short-lived syndicated daytime talk show; Johnny Carson was her first guest. In the middle of the 1960s, she released at least two comedy albums, The Next to Last Joan Rivers Album and Joan Rivers Presents Mr. Phyllis & Other Funny Stories.

By the 1970s, Rivers was appearing on various television comedy and variety shows, including The Carol Burnett Show and a semi-regular stint on Hollywood Squares. From 1972 to 1976, she narrated The Adventures of Letterman, an animated segment for The Electric Company. In 1973, Rivers wrote the TV movie The Girl Most Likely to..., a black comedy starring Stockard Channing. In 1978, Rivers wrote and directed the film Rabbit Test, starring her friend Billy Crystal. During the same decade, she was the opening act for singer Helen Reddy on the Las Vegas Strip. In July 1970, Rivers performed as the opening act for Sergio Franchi during an acclaimed appearance at the Mill Run Theater in Chicago and also opened for Franchi at the MGM Grand Hotel from 1974-1976. Rivers became a Las Vegas Strip headliner herself in the 1980s.

This is a pretty nice Joan Rivers autograph on a program from the Playbill for the Broadway musical, 'Sally Marr'. This includes the full program in it's entirety autographed by Joan Rivers. It is in wonderful condition and priced to sell fast!