pharmachologic effect
Pharmacological action - antianginal, angioprotective, antihypoxic, cardioprotective.

Pharmacokinetics
After oral administration, the drug is rapidly absorbed, bioavailability is 78%. Cmax in blood plasma is reached within 1-2 hours after ingestion. It is metabolized in the body mainly in the liver with the formation of 2 main metabolites, which are excreted by the kidneys. T1 / 2 when taken orally depends on the dose, is 3-6 hours.

Indications for use
Common to two dosages

reduced performance, mental and physical overload.

For a dosage of 500 mg additionally

in the complex therapy of ischemic heart disease (angina pectoris, myocardial infarction), chronic heart failure and dyshormonal cardiomyopathy, as well as in the complex therapy of subacute and chronic disorders of the blood supply to the brain (after a stroke, cerebrovascular insufficiency);

withdrawal syndrome in chronic alcoholism (in combination with specific therapy).